Diethylene glycol can be used as a gas dehydration agent, aromatic hydrocarbon extraction solvent, key raw material in polyurethane synthesis, solvent, humectant, etc., and can also serve as an intermediate for synthesizing other organic compounds, flavors, and pharmaceuticals. This dataset includes primary raw and auxiliary materials, energy inputs, and waterborne emissions associated with the production process; however, infrastructure such as production equipment and plant construction are not included within the system boundaries of the dataset. The life cycle inventory is compiled from data sourced from multiple references. The diethylene glycol is produced via ethane oxidation process, and the production process includes feedstock preparation, catalyst application, product recovery, purification, and impurity removal steps.