Butyl rubber sealing plugs are used in pharmaceuticals, food, adhesives, waterproof membranes, tire inner lining plates, and other fields. The average weight of the butyl rubber sealing plug is about 1.1 g, with an outer diameter of approximately 11 mm and a thickness of about 3.75 mm. This dataset includes major raw and auxiliary materials, energy consumption, atmospheric emissions, and waste generated during the production process. Infrastructure such as production equipment manufacturing and factory construction are excluded from the system boundary. The life cycle inventory is compiled from data obtained from multiple sources. The production process of rubber sealing plugs includes slicing, feeding, mixing, extrusion, open milling, molding, polishing, cleaning, drying, and inspection procedures.