Methyl tert-butyl ether (MTBE) is primarily used as a gasoline additive, possessing excellent anti-knocking properties and effectively increasing octane ratings. It can also be cracked to produce isobutylene. MTBE exhibits good miscibility with gasoline, absorbs little water, and is environmentally benign. It is used as an analytical solvent and extraction agent, particularly as a mobile phase in chromatography, especially high-performance liquid chromatography (HPLC). It forms azeotropes with certain polar solvents such as water, methanol, and ethanol. Additionally, MTBE has a mild anesthetic effect.